6. David Duchovny
The man was such a fan of Shandling, David Duchovny appeared in not one, but three episodes. He played himself, but his persona on the show suffered a man-crush on Sanders. Then, the unthinkable happened. Shandling appeared on an episode of “The X-Files,” where Duchovny played Fox Mulder. His character’s partner, Scully, played by Gillian Anderson, remarks, “I think that Shandling likes you a bit, too.”